Bidirectional FHIR–OMOP CDM Transformations using TermX for Real-World Data Secondary Use
Towards Bidirectional FHIR–OMOP CDM Transformations Using TermX to Support the
A study was conducted on developing bidirectional transformations between FHIR and OMOP CDM using TermX.
Summary
This study developed and validated bidirectional data transformation rules between HL7 FHIR and OMOP CDM using the open-source platform TermX. This demonstrates a methodology for mapping clinical care data (FHIR) into standardized models suitable for secondary use, addressing interoperability challenges in digital health.
Key Players
Details
The research addresses the challenge of utilizing vast amounts of accumulated but underutilized healthcare data (real-world data) for secondary purposes. Specifically, it tackles the transformation gap between HL7 FHIR, the standard for clinical information exchange, and OMOP CDM, a reference model designed for secondary use. The authors utilized TermX, an open-source terminology and data interoperability platform, to develop bidirectional mapping rules between these two standards. They developed and validated standardized transformation rules, focusing on vital signs data. The evaluation demonstrated that the resulting rules achieved 74% mapping coverage from FHIR to OMOP CDM tables, with partial mapping also established in the reverse direction. This outcome proves the feasibility of reusable, standards-based transformations for addressing structural and semantic interoperability challenges. This work contributes significantly to advancing digital health interoperability, particularly supporting objectives like those set by the European Health Data Space (EHDS).
Technology Note
FHIR（Fast Healthcare Interoperability Resources）は医療データ交換の国際標準。このエントリの関連技術: HL7
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