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HL7 Standards: From v2 to FHIR in Digital Health

HL7 standards: from v2 to FHIR in digital health - Teoresi Group

June 12, 2026

Summary

To address the challenges of medical information sharing, HL7 standards have continuously evolved. This article compares and explains the evolution from message-based HL7 v2, through HL7 v3 with a more advanced semantic structure, to FHIR's web-based approach using RESTful APIs.

Details

A key challenge in digital health is the exchange of clinical data among systems and devices, for which HL7 standards serve as a crucial reference point. This technical article traces the historical evolution of data interoperability by comparing three versions: HL7 v2, v3, and FHIR. HL7 v2 utilizes a widely adopted message-based model for exchanging clinical and administrative data. It evolved into HL7 v3, which features a more advanced semantic structure. Most notably, FHIR represents the modern web-based approach, designed to integrate clinical and administrative resources through RESTful APIs. Each version responds to different technological and organizational needs. Reading this article provides deep insight into the characteristics and evolutionary background of each model.

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